Estero Island is located near Cape Coral and Fort Myers, between Sanibel Lighthouse and Lovers Key State Park. We have nearly 3 dozen homes in the mid-island region of Estero Island, all within just a few minutes of Fort Myers Beach. The rentals are a mix of private homes and condos, ranging in price from $60 a night to $260 a night. Amenities may include pools, tennis courts, shuffleboard, private lanai, BBQ grills, and more. If you want to be near both ends of the island so that you can easily visit Sanibel Lighthouse and Lovers Key State Park, whether by car or by boat, then the mid-island region is the best option to find your perfect vacation rental for your trip to Fort Myers Beach, Florida.